Panthers vs Saints: Odds for Week 10

Panthers vs Saints Odds: Who Is Favored To Win?

Here are the opening odds for the Panthers vs Saints Week 10 matchup. According to DraftKings, Carolina has a 71.0% chance to win, which isn’t surprising given the game is at home and the Panthers hold a much better record.

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Panthers vs Saints Spread: What It Means

The 5.5‑point spread shows that oddsmakers expect the Panthers to win by about a touchdown. If you’re betting on Carolina, they’ll need to win by at least 6 points for your ticket to cash. On the flip side, Saints backers would need New Orleans to either win the game or keep the loss within 5 points. I expect Carolina to get the win, but anything’s possible in a divisional matchup.

Panthers vs Saints Moneyline: What To Know

The Panthers sit at -245 on the moneyline, making them the clear favorites in their Week 10 matchup against the Saints. That means you’d have to risk more to get a solid payout. Meanwhile, the Saints are at $200, so a $100 bet on New Orleans would win you a total of $300 if they pull off the upset. At those odds, the Saints have a 33.3% chance to win outright.

Panthers Chances To Win vs Saints

The Panthers’ roster looks much stronger this year, giving them an edge over their NFC South rivals. Hosting the first matchup, Carolina is expected to come away with a win. New Orleans faces an uphill battle with a new head coach, rookie quarterback, and a 1–8 record. Coming off an upset win over the Packers, if the Panthers carry that momentum into Sunday, they should have no problem covering the spread.

How The Panthers Win vs Saints

Carolina can take down the Saints if the offensive line gives Bryce Young the time he needs to make plays and opens lanes for Rico Dowdle to gain yards. On defense, the Panthers are much improved from last season. If they can pressure New Orleans’ passing game, Carolina should have a well‑balanced team ready to take on the Saints.

• 📈 Strength: Running back Rico Dowdle and WR Tetra McMillan make the Panthers’ offensive attack even stronger.
• 📉 Weakness: The rivalry with the Saints could make Carolina vulnerable despite New Orleans’ struggles.

How The Saints Win vs Panthers

The Saints have a new head coach and quarterback and are in the middle of a rebuild, which hasn’t gone smoothly. But if they can put together a solid performance, the Saints could exploit Carolina’s vulnerabilities and steal the game. That’s where New Orleans’ defense will play a key role.

• 📈 Strength: Rookie QB Tyler Shough’s downfield passing could challenge the Panthers’ defense.
• 📉 Weakness: The Saints have struggled to establish a consistent running game, leaving them one-dimensional.

History of Panthers Saints Games

The Panthers and Saints have played 60 times in the regular season and once in the postseason. The Saints lead the series 32-29. Carolina is 14-17 on the road against New Orleans and 15-15 at home.

All-Time Best Panthers Saints Games

The Saints and Panthers have had some incredible matchups over the last few decades. Here are some of the most memorable contests:

Game 1: 1-7-2018 (2017 NFC Wild Card Round)

The Saints and Panthers met in the 2017 NFL Playoffs for the first time in NFL history. The Saints jumped out to a 21-9 lead going into halftime, and a few late scores by the Panthers allowed them to sneak back into the game. However, the Saints would win 31-26 and would advance to Round 2 of the NFL playoffs.

Game 2: 10-16-2016 (Week 6)

This was one of the highest-scoring games in the rivalry, with 79 total points scored. This was a fantastic matchup between Cam Newton and Drew Brees in their primes, with the Saints getting the 41-38 win. Drew Brees threw for 465 yards and four touchdowns, which was one of his best performances in the NFL.

Game: 10-26-2003 (Week 8)

The Panthers and Saints have not played many overtime games, but this was one to remember in 2003. The Saints scored 17 points in the second quarter to jump out to a 17-10 lead at halftime. But both teams only managed to score field goals in the second half, and it was a 31-yard field goal by John Casey of the Panthers that ultimately ended this game. The Panthers would get the win and advance to 6-1 on the season and would eventually make it to the Super Bowl, losing to the Patriots.

Other Matchups This Season

How Far Will The Panthers Go This Season?

Author

Brandon Justice

@BrandonJustice_

Brandon Justice is a Writer, Commercial Editor, and Fact Checker for BetCarolina.com. He's covered numerous sports betting perspectives for over six years, including everything from analysis & daily picks to reviews & guides. Additionally, he spent six seasons covering college football. The Carolina Panthers follow him on Twitter.