Who has the Best Odds to Win March Madness?
The Duke Blue Devils have the best odds to win March Madness. Here are the current Top 6 March Madness Odds according to FanDuel in North Carolina:
| Team | Odds |
|---|---|
| 🏀 Duke | +220 |
| 🏀 Florida | +390 |
| 🏀 Houston | +550 |
| 🏀 Auburn | +550 |
| 🏀 Alabama | +1600 |
| 🏀 Tennessee | +1600 |
| ✅ Last Updated: | March 25, 2025 |
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Latest Updates Impacting March Madness Odds: March 25, 2025
Last year's March Madness college basketball did not disappoint.
National Championship Storylines:
- Oddsmakers list Duke as the favorite to win it this season.
- Auburn is also among the favorites to make it to the national championship.
Final Four Storylines:
- Which team will be the surprise of the Final Four this season?
- Houston and Florida are the two favorites, besides Duke and Auburn, to be favorited to make it all the way to the Final Four.
Elite Eight Storylines:
- Three of four top seeds make it to the Elite Eight every season, giving the top teams a 75% chance of making it.
- N.C. State was the surprise winner in the Elite Eight last season.
- Only two No. 1 seeds appeared in the Elite Eight last season.
Sweet 16 Storylines:.
- All four No. 1 seeds are in the Sweet 16 this season.
- No. 1-seeded Houston will battle No. 4-seeded Purdue.
- No. 1-seeded Auburn will face No. 5-seeded Michigan.
- No. 1-seeded Florida will clash with No. 4-seeded Maryland.
- No. 1-seeded Duke, the favorite on DraftKings and other sportsbooks to win it all, will face No. 4-seeded Arizona in the Sweet 16.
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Round of 32 Storylines:
- Four underdogs made it to the Round of 32, with three falling to the favorites.
- New Mexico looks to make it to the Round of 32 for the first time in 13 years.
- No. 1-seeded Florida wins a 77-75 thriller, barely escaping the defending champion UConn to advance to the Sweet 16.
- No. 1-seeded Auburn takes down No. 9-seeded Creighton to advance to the Sweet 16.
- No. 4-seeded Purdue takes down No. 12-seeded McNeese, erasing any hope of a Cinderella run.
- No. 6-seeded BYU makes a final stop, beating No. 3-seeded Wisconsin to advance to the Sweet 16.
- No. 10-seeded Arkansas shocked No. 3-ranked St. Johns 75-66, making it to the Sweet 16 to battle Texas Tech.
- No. 3-seeded Houston, and one of the favorites to win it all, defeats No. 8-seeded Gonzaga in the Round of 32 top advance to the Sweet 16.
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Round of 64 Storylines:
- Which underdog has the best chance to impact this season's tournament?
- Last year's champion, UConn, will enter the Round of 64 as the No. 8 seed in the East/Raleigh Bracket and will face No. 9 seed Oklahoma.
- Florida, who has +380 odds to win it all, will start the Round of 64 against No. 16 seed Norfolk State.
- No. 10-ranked Arkansas stuns No. 7-ranked Kansas 79-72, sending the Jayhawks home.
- No. 12-ranked McNeese won their first-ever NCAA Tournament game with a stunning upset over Clemson in the Round of 64.
- 2022 champion Auburn started the Round of 64 as the No. 1 seed in the South/Atlanta bracket, starting their goal of winning its second title in four seasons with a victory over No. 16 Alabama State.
- Louisville returned to the NCAA Tournament for the first time in six years but fell to No. 9-seed Creighton in the Round of 64.
- No. 11-ranked Drake pulls off an upset over No. 6-ranked Missouri, sending them home in the Round of 64.
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How the UConn Huskies Won 2024 March Madness
UConn's roster was loaded with players who had more tournament experience than any team, and they played with exceptional chemistry.
UConn finished the season ranked 9th in the NCAA in scoring defense, allowing just 63.4 points per game. Coupled with the 23rd-best offensive production, a mix of solid offense and stout defense was a recipe for major success.
At 31-3 on the regular season, the Huskies had long been the favorite to win the East Region—and the National Championship.
UConn routed Stetson 91-52 in the tournament's first game, handled Northwestern 75-58 to advance to the Sweet 16, crushed Illinois 77-52 in the Elite Eight, and put away Alabama 86-72 in the Final Four.
The defending National Champions were led by head coach Dan Hurley and experienced senior guards Cam Spencer and Tristian Newton, both of whom average over 14 points a game. Three potential first-round NBA draft picks (center Donovan Clingan, guard Stephon Castle, and forward Alex Karaban) brought additional firepower for the Huskies to compete with any team in college basketball.
How To Bet On March Madness
There are a variety of ways to bet on March Madness, including futures and individual game-by-game spreads. You can also bet on teams strictly to make the Final Four and make prop bets.
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March Madness Futures March Madness futures are fun to play because they allow you options to bet on a variety of teams. If you have a few long-shot teams and one or two of them make it to the Sweet 16 or Elite Eight, you have great hedging opportunities. Or you can bet on second-tier contenders, like Marquette and Illinois. -
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March Madness Spreads March Madness spreads are exciting because they are available on every game. You are betting on which team will cover the spread, not win the game outright, so even a No. 16 seed has a chance to cover against a No. 1 seed, for example. -
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March Madness Props March Madness prop bets allow you to bet on specific things for players in games, such as how many rebounds or points a player will have. You can bet on Purdue's Zach Edey to go over/under 17.5 points, for example. This allows bettors to exploit certain matchups within the game. -
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March Madness Bracket Challenges March Madness bracket challenges are a fun way to get a little skin in the game. You select the winner of all 63 games of the tournament before it begins and then get to follow along as the tournament rolls along. If you need suggestions for your March Madness bracket names, we've got you covered.
March Madness Odds FAQ
The Duke Blue Devils have the best odds to win March Madness in 2025. FanDuel lists Duke's 2024-25 odds at +220 to win the NCAA Tournament next season. Translated to implied probability, Duke has a 31.2% chance to win it.
The 2025 NCAA men's Final Four will be held at the Alamodome in San Antonio, Texas this season. The University of Texas at San Antonio and the University of Incarnate Word will host the Final Four over two days.
March Madness starts on March 18 with the first play-in games and ends on April 5 with two Final Four games. The tournament truly ends on April 7 at the Alamodome, with the two best teams in college basketball squaring off.
Author
Robert B. Hayek has been writing about sports for over a decade and is currently a member of the Gambling.com Group team. In his spare time, he runs the largest sports meetup group in Orange County, CA, actively participating in every sport imaginable. He is also a published author of five thriller novels, all available on Amazon.
