Who has the Best Odds to Win March Madness?
The Duke Blue Devils have the best odds to win March Madness. Here are the current National Championship Odds, according to FanDuel in North Carolina:
| Team | Odds |
|---|---|
| 🏀 Duke | +1000 |
| 🏀 Houston | +1200 |
| ✅ Last Updated: | April 14, 2025 |
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Latest Updates Impacting March Madness Odds: April 14, 2025
Last year's March Madness college basketball did not disappoint.
National Championship Storylines:
- Florida defeated Houston 65-63 to secure its third championship.
- Oddsmakers list Duke as the favorite to win it next season.
Final Four Storylines:
- Houston stunned Duke, rallying from a 14-point deficit to win their Final Four matchup 70-67.
- Duke failed to make it to the National Championship for the first time since 2015.
- Florida defeated Auburn to make it to the National Championship for the first time since 2007.
- Auburn once again fell short, as they still have never made it to a championship.
Elite Eight Storylines:
- Only two No. 1 seeds appeared in the Elite Eight last season.
- All four No. 1 seeds win their Elite Eight showdowns, becoming the first set of top-seeded teams to advance to the Final Four since 2016.
- No. 1-seeded Florida defeated No. 3-seeded Texas Tech 84-79.
- No. 1 seed Duke routed No. 2 seed Alabama 85-65.
Sweet 16 Storylines:.
- All four No. 1 seeds are in the Sweet 16 this season.
- No. 1-seeded Houston will battle No. 4-seeded Purdue.
- No. 1-seeded Auburn will face No. 5-seeded Michigan.
- No. 1-seeded Florida blows out No. 4-seeded Maryland 87-71 to advance to the Elite Eight and will face No. 3-seeded Texas Tech.
- No. 1-seeded Duke, the favorite on DraftKings and other sportsbooks to win it all, defeats No. 4-seeded Arizona 100-93 in the Sweet 16 to advance to the Elite Eight to play No. 2-seeded Alabama.
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Round of 32 Storylines:
- Four underdogs made it to the Round of 32, with three falling to the favorites.
- No. 1-seeded Florida wins a 77-75 thriller, barely escaping the defending champion UConn to advance to the Sweet 16.
- No. 1-seeded Auburn takes down No. 9-seeded Creighton to advance to the Sweet 16.
- No. 4-seeded Purdue takes down No. 12-seeded McNeese, erasing any hope of a Cinderella run.
- No. 6-seeded BYU makes a final stop, beating No. 3-seeded Wisconsin to advance to the Sweet 16.
- No. 10-seeded Arkansas shocked No. 3-ranked St. Johns 75-66, making it to the Sweet 16 to battle Texas Tech.
- No. 3-seeded Houston, and one of the favorites to win it all, defeats No. 8-seeded Gonzaga in the Round of 32 top advance to the Sweet 16.
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Round of 64 Storylines:
- Which underdog has the best chance to impact this season's tournament?
- Last year's champion, UConn, will enter the Round of 64 as the No. 8 seed in the East/Raleigh Bracket and will face No. 9 seed Oklahoma.
- Florida, who has +380 odds to win it all, will start the Round of 64 against No. 16 seed Norfolk State.
- No. 10-ranked Arkansas stuns No. 7-ranked Kansas 79-72, sending the Jayhawks home.
- No. 12-ranked McNeese won their first-ever NCAA Tournament game with a stunning upset over Clemson in the Round of 64.
- 2022 champion Auburn started the Round of 64 as the No. 1 seed in the South/Atlanta bracket, starting their goal of winning its second title in four seasons with a victory over No. 16 Alabama State.
- Louisville returned to the NCAA Tournament for the first time in six years but fell to No. 9-seed Creighton in the Round of 64.
- No. 11-ranked Drake pulls off an upset over No. 6-ranked Missouri, sending them home in the Round of 64.
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How the Florida Gators Won 2025 March Madness
Florida's roster was ready for a good run, and it showed up when they absolutely needed it, running through the NCAA Tournament, and completing the path to becoming the 2025 National Champions.
Florida finished the season ranked third in NCAA in points per game, averaging 84.8 points. They did this despite ranking 45th in field-goal shooting percentage, including 82nd from beyond the arc. To compensate for this, the Gators were stingy on defense, ranking 12th in opponent field-goal shooting percentage, including fifth on defending the three-point shot.
At 36-4 on the regular season, the Gators were one of the favorites to win the Southeastern Conference—and the National Championship.
Floridan routed Norfolk State 91-52 in the tournament's first game, edged out the previous champion UConn 77-75 to advance to the Sweet 16, and demolished Maryland 87-71 to advance to the Elite Eight. Then, they took down Texas Tech 84-79 to give themselves a spot in the Final Four. Florida then ousted Auburn 79-73 in the Final Four before rallying to stun the Cougars 65-63 in the 2025 National Championship.
The defending National Champions were led by head coach Todd Golden and senior guards Walter Clayton Jr., Alijah Martin, and Will Richard, all of whom are three potential NBA stars, along with potential first-round draft pick Alex Condon.
How To Bet On March Madness
There are a variety of ways to bet on March Madness, including futures and individual game-by-game spreads. You can also bet on teams strictly to make the Final Four and make prop bets.
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March Madness Futures March Madness futures are fun to play because they allow you options to bet on a variety of teams. If you have a few long-shot teams and one or two of them make it to the Sweet 16 or Elite Eight, you have great hedging opportunities. Or you can bet on second-tier contenders, like Marquette and Illinois. -
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March Madness Spreads March Madness spreads are exciting because they are available on every game. You are betting on which team will cover the spread, not win the game outright, so even a No. 16 seed has a chance to cover against a No. 1 seed, for example. -
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March Madness Props March Madness prop bets allow you to bet on specific things for players in games, such as how many rebounds or points a player will have. You can bet on Purdue's Zach Edey to go over/under 17.5 points, for example. This allows bettors to exploit certain matchups within the game. -
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March Madness Bracket Challenges March Madness bracket challenges are a fun way to get a little skin in the game. You select the winner of all 63 games of the tournament before it begins and then get to follow along as the tournament rolls along. If you need suggestions for your March Madness bracket names, we've got you covered.
March Madness Odds FAQ
The Duke Blue Devils have the best odds to win March Madness in 2026, despite falling in the Final Four to Houston in 2025. Oddsmakers like their chances to complete their championship goal and secure the 2026 National Championship.
The 2026 NCAA men's Final Four will be held at Lucas Oil Stadium in Indianapolis, Indiana. The Horizon League and IU Indianapolis will host it.
March Madness started on March 18 with the first play-in games and will end on April 5 with two Final Four games. The tournament ended on April 7 at the Alamodome, with the two best teams in college basketball squaring off.
The Florida Gators won the March Madness tournament in 2025, defeating Houston in the final game by a score of 65-63. The game was played in San Antonio, Texas. It was Florida's third championship and first since the 2007 season.
Author
Robert B. Hayek has been writing about sports for over a decade and is currently a member of the Gambling.com Group team. In his spare time, he runs the largest sports meetup group in Orange County, CA, actively participating in every sport imaginable. He is also a published author of five thriller novels, all available on Amazon.
